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Department of Pathology and Cell Regulation (PCR) Kyoto Prefectural University of Medicine |
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-Publications-
Original articles Tamura S*, Mochizuki K*, Kumamoto Y, Morishita Y, Yamanaka M, Ho WJ, Harada Y, Fujita K, Tanaka H. (*equally contributed) Phase-targeting rapid cryofixation of the beating heart and histological analysis unveil contractile state-dependent sarcomere dynamics. Sci. Rep., 16, 11484 (2026) Nakao R, Honda M, Mitsugi N, Nagata H, Harada Y. Fulminant Food Aspiration-Induced Pneumonia Leading to Tension Pyopneumothorax after Proctectomy: An Autopsy Case Surg. Case Rep., 12, 25-0529 (2026) Kondo R, Mizuno Y, Mochizuki K, Hashimoto K, Clement J.E, Kumamoto Y, Fujita K, Harada Y, Komatsuzaki T. Integrating spatial and chemical information enhances differentiation of non-alcoholic steatohepatitis states in Raman Imaging Sci.Rep., 15, 35216 (2025) Tsuji K, Yamanaka M, Kumamoto K, Tamura S, Miyamura W, Kubo T, Mizushima K, Kono K, Hirano H, Shiozaki M, Zhao X, Xi H, Sugiura K, Fukushima S, Kunimoto T, Tanabe Y, Nishida K, Mochizuki K, Harada Y, Smith NI, Heintzmann R, Yu Z, Wang MC, Nagai T, Tanaka H, Fujita K. Time-deterministic cryo-optical microscopy Light: Sci. Appl., 14, 275 (2025) Pelissier A*, Hashimoto K*, Mochizuki K*, Taylor JN, Clement JE, Kumamoto Y, Fujita K, Harada Y, Komatsuzaki T. (*equally contributed) Beyond the Nucleus: Cytoplasmic Dominance in Follicular Thyroid Carcinoma Detection Using Single-Cell Raman Imaging across Mutiple Devices Anal. Chem., 97, 12998-13009 (2025) Sawai Y*, Hayakawa M*, Yasuda H, Nakao R, Ogata T, Nakamura A, Mochizuki K, Takata T, Miyake H, Sogame Y, Morimura R, Kurahashi T, Dai P, Konishi E, Itoh Y, Tanaka H, Harada Y. (*equally contributed) Oleic acid enhances the proliferation of gallbladder cancer cells via the GPR120/ERK pathway Biochem. Biophys. Res. Commun., 754, 151530 (2025) Koyama Y*, Nakao R*, Sato J, Honda M, Inamori O, Tanaka N, Morinaga Y, Konishi E, Harada Y, Tanaka H, Yasuda H, Itoh Y, Nagahara H, Niioka H, Takamatsu T. (*equally contributed) H&E Style Translation Using CycleGAN for Deep Ultraviolet-Excitation Fluorescence Images of Pancreatic Endoscopic Ultrasound-Fine Needle Aspiration/Biopsy Toward Slide-Free Rapid Patology Acta Histochem. Cytochem., 58, 59-67 (2025) Mizushima K, Kumamoto Y, Tamura S, Yamanaka Y, Mochizuki K, Li M, Egochi S, Dodo K, Harada Y, Smith NI, Sodeoka M, Tanaka H, Fujita K. Raman microscopy of cryofixed biological specimens for high-resolution and high-sensitivity chemical imaging Sci.Adv., 10, eadn0110 (2024) Minamikawa T, Sakaguchi R, Harada Y, Tanioka H, Inoue S, Hase H, Mori Y, Takamatsu T, Yamasaki Y, Morimoto Y, Kawasaki Ma, Kawasaki Mi. Long-range enhancement for fluorescence and Raman spectroscopy using Ag nanoislands protected withy column-structured silica overlayer Light: Sci. Appl., 13, 299 (2024) Takata T, Nakamura A, Yasuda H, Miyake H, Sogame Y, Sawai Y, Hayakawa M, Mochizuki K, Nakao R, Ogata T, Ikoma H, Konishi E, Harada Y, Otsuji E, Itoh Y, Tanaka H. Pathophysiological Implications of Protein Lactylation in Pancreatic Epithelial Tumors Acta Histochem. Cytochem., 57, 57-66 (2024) Tabata K, Kawagoe H, Taylor JN, Mochizuki K, Kubo T, Clement JE, Kumamoto Y, Harada Y, Nakamura A, Fujita K, Komatsuzaki T. On-the-fly Raman microscopy guaranteeing the accuracy of discrimination Proc. Natl. Acad. Sci. U.S.A., 121, e2304866121 (2024) Tsuji Y, Ogata T, Mochizuiki K, Tamura S, Morishita Y, Takamatsu T, Matoba S, Tanaka H. Myofibroblasts impair myocardial impulse propagation by heterocellular connexin43 gap-junctional coupling through micropores Front. Physiol., 15, 1352911 (2024) Mochizuki K, Kumamoto Y, Maeda S, Tanuma M, Kasai A, Takemura M, Harada Y, Hashimoto H, Tanaka H, Smith NI, Fujita K. High-throughput line-illumination Raman microscopy with multislit detection Biomed. Opt. Express, 14, 1015-1026 (2023) Helal KM, Cahyadi H, Taylor JN, Okajima A, Tabata K, Kumamoto Y, Mochizuki K, Itoh Y, Takamatsu T, Tanaka H, Fujita K, Komatsuzaki T, Harada Y. Raman imaging of rat non-alcoholic fatty liver tissues reveals distinct biomolecular states FEBS Lett., 597, 1517-1527 (2023) Bhuiyan AH, Clement JE, Ferdous Z, Mochizuki K, Tabata K, Taylor JN, Kumamoto Y, Harada Y, Bocklitz T, Fujita K, Komatsuzaki T. Differentiability of cell types enhanced by detrending a non-homogeneous pattern in a line-illumination Raman microscope Analyst, 148, 3574-3583 (2023) Taylor JN, Pelissier A, Mochizuki K, Hashimoto K, Kumamoto Y, Harada Y, Fujita K, Bocklitz T, Komatsuzaki T. Correction for Extrinsic Background in Raman Hyperspectral Images Anal. Chem., 95, 12298-12305 (2023) Hayakawa M, Taylor JN, Nakao R, Mochizuki K, Sawai Y, Hashimoto K, Tabata K, Kumamoto Y, Fujita K, Konishi E, Hirano S, Tanaka H, Komatsuzaki T, Harada Y. Lipid droplet accumulation and adipophilin expression in follicular thyroid carcinoma Biochem. Biophys. Res. Commun. 640, 192-201 (2023) Morishita Y, Tamura S, Mochizuki K, Harada Y, Takamatsu T, Hosoi H, Tanaka H. Generation of myocyte agonal Ca2+ waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation Sci. Rep. 13, 803 (2023) Sato J, Matsumoto T, Nakao R, Tanaka H, Nagahara H, Niioka H, Takamatsu T. Deep UV-excited fluorescence microscopy installed with CycleGAN-assisted image translation enhances precise detection of lymph node metastasis towards rapid intraoperative diagnosis. Sci. Rep., 13, 21363 (2023) Takemura M*, Mochizuki K*, Harada Y, Okajima A, Hayakawa M, Dai P, Itoh Y, Tanaka H. (*equally contributed) Label-free Assessment of the Nascent State of Rat Non-alcoholic Fatty Liver Disease Using Spontaneous Raman Microscopy Acta Histochem. Cytochem. 55, 57-66 (2022) Harada Y, Sogame Y, Nakao R, Ogata T, Yasuda H, Sakagami J, Itoh Y, Tanaka H. Autopsy of a Patient with Primary Pancreatic Lymphoma with Findings Resembling Severe Acute Pancreatitis Int. Med. 0757-22 (2022) Harada Y, Murayama Y, Takamatsu T, Otsuji E, Tanaka H Fluorescence Imaging for Tumor Detection: Recent Advances and Challenges Int. J. Mol. Sci. 23, 6478 (2022) Beika M, Harada Y, Minamikawa T, Yamaoka Y, Koizumi N, Murayama Y, Konishi H, Shiozaki A, Fujiwara H, Otsuji E, Takamatsu T, Tanaka H. Accumulation of Uroporphyrin I in Necrotic Tissues of Squamous Cell Carcinoma after Administration of 5-Aminolevulinic Acid Int. J. Mol. Sci. 22, 10121 (2021) Ikemoto K, Hashimoto K, Harada Y, Kumamoto Y, Hayakawa M, Mochizuki K, Matsuo K, Yashiro K, Yaku H, Takamatsu T, Tanaka H. Raman Spectroscopic Assessment of Myocardial Viability in Langendorff-Perfused Ischemic Rat Hearts Acta Histochem. Cytochem. 54, 65-72 (2021) Nishida K, Sato H, Oketani R, Mochizuki K, Temma K, Kumamoto Y, Tanaka H, Fujita K. Using saturated absorption for superresolution laser scanning transmission microscopy J. Microsc. 1-13 (2021) Matsumoto T, Niioka H, Kumamoto Y, Sato J, Inamori O, Nakao R, Harada Y, Konishi E, Otsuji E, Tanaka H, Miyake J, Takamatsu T. Deep-UV excitation fluorescence microscopy for detection of lymph node metastasis using deep neural network Sci. Rep. 9, 16912 (2019) Nishi M, Ogata T, Cannistraci CV, Ciucci S, Nakanishi N, Higuchi Y, Sakamoto A, Tsuji Y, Mizushima K, Matoba S. Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin-4 Deletion Against Ischemia/Reperfusion Injury. J. Am. Heart Assoc. 8, e012047 (2019). Morita M, Hideo T, Kumamoto Y, Nakamura A, Harada Y, Ogata T, Sakaguchi K, Taguchi T, Takamatsu T. Fluorescence-based discrimination of breast cancer cells by direct exposure to 5-aminolevulinic acid. Cancer Med. 2019 (Epub ahead of print). Kumamoto Y, Matsumoto T, Tanaka H, Takamatsu T. Terbium ion as RNA tag for slide-free pathology with deep-ultraviolet excitation fluorescence. Sci. Rep. 9, 10745 (2019). Helal KM, Taylor JN, Cahyadi H, Okajima A, Tabata K, Itoh Y, Tanaka H, Fujita K, Harada Y, Komatsuzaki T. Raman spectroscopic histology using machine learning for nonalcoholic fatty liver disease. FEBS Lett. 2019 (Epub ahead of print). Taylor JN, Mochizuki K, Hashimoto K, Kumamoto Y, Harada Y, Fujita K, Komatsuzaki T. High-resolution Raman microscopic detection of follicular thyroid cancer cells with unsupervised machine learning. J. Phys. Chem. B 123, 4358-4372 (2019). Kumamoto Y, Mochizuki K, Hashimoto K, Harada Y, Tanaka H, Fujita K. High-throughput cell imaging and classification by narrowband and low-spectral-resolution Raman microscopy. J. Phys. Chem. B 123, 2654-2661 (2019). Selected for the cover art of J. Phys. Chem. B 123, 30. Puppulin L, Hosogi S, Sun H, Matsuo K, Inui T, Kumamoto Y, Suzaki T, Tanaka H, Marunaka Y. Bioconjugation strategy for cell surface labeling with gold nanostructures designed for highly localized pH measurement. Nat. Commun. 9, 5278 (2018). Yamamoto T, Minamikawa T, Harada Y, Yamaoka Y, Tanaka H, Yaku H, Takamatsu T. Label-free evaluation of myocardial infarct in surgically excised ventricular myocardium by Raman spectroscopy. Sci. Rep. 8, 14671 (2018). Liu HL, Yang T, Tatsumi Y, Zhang Y, Dong B, Guo H, Zhang Z, Kumamoto Y, Li MY, Li LJ, Saito R, Kawata S. Deep-ultraviolet Raman scattering spectroscopy of monolayer WS2. Sci. Rep. 8, 11398 (2018). Fujita Y, Kishimoto M, Dohi O, Kamada K, Majima A, Kimura-Tsuchiya R, Yagi N, Konishi H, Naito Y, Harada Y, Tanaka H, Konishi E, Sugai T, Yanagisawa A. How to adjust endoscopic findings to histopathological findings of the stomach: a "histopathology-oriented" correspondence method helps to understand endoscopic findings. Gastric Cancer 21, 573-577 (2018). Matsuyama T, Tanaka H, Ishibashi-Ueda H, Takamatsu T. Spatiotemporally non-uniform Ca2+ dynamics of cardiac Purkinje fibers in mouse myocardial infarct. J. Histochem. Cytochem. 65, 655-667 (2017). Matsuo H, Harada Y, Minamikawa T, Kato Y, Murayama Y, Otsuji E, Takamatsu T, Tanaka H. Efficient fluorescence detection of protoporphyrin IX in metastatic lymph nodes of murine colorectal cancer stained with indigo carmine. Photodiag. Photodyn. Therapy 19, 175-180 (2017). Puppulin L, Pezzotti G, Sun H, Hosogi S, Nakahari T, Inui T, Kumamoto Y, Tanaka H, Marunaka Y. Raman micro-spectroscopy as a viable tool to monitor and estimate the ionic transport in epithelial cells. Sci. Rep. 7, 3395 (2017). Ohira S, Tanaka H, Harada Y, Minamikawa T, Kumamoto Y, Matoba S, Yaku H, Takamatsu T. Label-free detection of myocardial ischaemia in the perfused rat heart by spontaneous Raman spectroscopy. Sci. Rep. 7, 42401 (2017). Kumamoto Y, Harada Y, Tanaka H, Takamatsu T. Rapid and accurate peripheral nerve imaging by multipoint Raman spectroscopy. Sci. Rep. 7, 845 (2017). Fujii M, Tanaka H, Nakamura A, Suzuki C, Harada Y, Takamatsu T, Hamaoka K. Histopathological characteristics of post-inflamed coronary arteries in Kawasaki disease-like vasculitis of rabbits. Acta Histochem. Cytochem. 49, 29-36 (2016). Koizumi N, Harada Y, Minamikawa T, Tanaka H, Otsuji E, Takamatsu T. Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid. World J. Gastroenterol. 22,1289-1296 (2016). Koizumi N, Harada Y, Beika M, Minamikawa T, Yamaoka Y, Dai P, Murayama Y, Yanagisawa A, Otsuji E, Tanaka H, Takamatsu T. Highly sensitive fluorescence detection of metastatic lymph @nodes of gastric cancer with photo-oxidation of protoporphyrin \. Eur. J. Surg. Oncol. 42, 1236-1246 (2016). Minamikawa T, Matsuo H, Kato Y, Harada Y, Otsuji E, Yanagisawa A, Tanaka H, Takamatsu T. Simplified and optimized multispectral imaging for 5-ALA-based fluorescence diagnosis of malignant lesions. Sci. Rep. 6, 25530 (2016). Mani H, Tanaka H, Adachi T, Ikegawa M, Dai P, Fujita N, Okuda T, Takamatsu T. How Dose the Ca2+-paradox injury induce contracture in the heart? -A combined study of the intracelluar Ca2+ dynamics and cell structures in perfused rat hearts - Acta Histochem. Cytochem. 48, 1-8 (2015). Dai P, Harada Y, Takamatsu T. Highy efficient direct conversion of human fibroblasts to neuronal cells by chemical compounds. J. Clin. Biochem. Nutr. 56, 166-170 (2015). Hino H, Dai P, Yoshida T, Hatakeyama T, Harada Y, Otsuji E, Okuda T, Takamatsu T. Interaction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27. Sci. Rep. 5,15365 (2015). Minamikawa T, Harada Y, Takamatsu T. Ex vivo peripheral nerve detection of rats by spontaneous Raman spectroscopy. Sci. Rep. 5, 17165 (2015). Nishiki-Muranishi N, Harada Y, Minamikawa T, Yamaoka Y, Dai P, Yaku H, Takamatsu T. Label-free evaluation of myocardinal infarction and its repair by spontaneous Raman spectroscopy. Anal. Chem. 86, 6903-10 (2014). Hamaoka-Okamoto A, Suzuki C, Yahata T, Ikeda K, Nagi-Miura N, Ohno N, Arai Y, Tanaka H, Takamatsu T, Hamaoka K. The involvement of the vasa vasorum in the development of vasculitis in animal model of Kawasaki disease. Pediatr. Rheumatol. 12, 12 (2014). Yamaoka Y, Harada Y, Sakakura M, Minamikawa T, Nishino S, Maehara S, Hamano S, Tanaka H, Takamatsu T. Photoacoustic microscopy using ultrashort pulses with two different pulse durations. Opt. Express 22, 17063-17072 (2014). Asai J, Harada Y, Beika M, Takenaka H, Katoh N, Takamatsu T. Photodynamic diagnosis of metastatic lymph nodes using 5-aminolevulinic acid in mouse squamous cell carcinoma. J. Dermatol. Sci. 74, 171-173 (2014). Miyawaki K, Harada Y, Wakabayashi N, Imaizumi N, Koizumi N, Nakano K, Yamaoka Y, Dai P, Itoh Y, Takamatsu T. In vivo detection of rat colorectal cancers by using a dual-wavelength excitation method. Acta Histochem. Cytochem. 47, 247-254 (2014). Daito J, Harada Y, Dai P, Yamaoka Y, Tamagawa-Mineoka R, Katoh N, Takamatsu T. Neutrophil phagocytosis of platelets in the early phase of 2,4,6-trinitro-1-chlorobenzene(TNCB)-induced dermatitis in mice. Acta Histochem. Cytochem. 47, 67-74 (2014). Jiang Y, Tanaka H, Matsuyama T, Yamaoka Y, and Takamatsu T. Pacing-induced non-uniform Ca2+ dynamics in rat atria revealed by rapid-scanning confocal microscopy. Acta Histochem. Cytochem. 47, 59-65 (2014). Minamikawa T, Harada Y, Koizumi N, Okihara K, Kamoi K, Yanagisawa A, Takamatsu T. Label-free detection of peripheral nerve tissues against adjacent tissues by spontaneous Raman microspectroscopy. Histochem. Cell Biol. 139, 181-93 (2013). Nakano K, Harada Y, Yamaoka Y, Miyawaki K, Imaizumi K, Takaoka H, Nakaoka M, Wakabayashi N, Yoshikawa T, Takamatsu T. Precise analysis of the autofluorescence characteristics of rat colon under UVA and violet light excitation. Curr. Pharm. Biotech. 14, 172-179 (2013). Suzuki T, Dai P, Hatakeyama T, Harada Y, Tanaka H, Yoshimura N, Takamatsu T. TGF- signaling regulates pancreatic -cell proliferation through control of cell cycle regulator p27 expression. Acta Histochem. Cytochem. 46, 51-58 (2013). Matsuyama T, Tanaka H, Adachi T, Jiang Y, Ishibashi-Ueda H, Takamatsu T. Intrinsic left atrial histoanatomy as the basis for reentrant excitation causing atrial fibrillation/flutter in rats. Heart Rhythm 10, 1342-8 (2013). Koizumi N, Harada Y, Murayama Y, Harada K, Beika M, Yamaoka Y, Dai P, Komatsu S, Kubota T, Ichikawa D, Okamoto K, Yanagisawa A, Otsuji E, Takamatsu T. Detection of metastatic lymph nodes using 5-aminolevulinic acid in patients with gastric cancer. Ann. Surg. Oncol. 20, 3541-8 (2013). Fujii H, Yamaguchi K, Ohnishi N, Sakamoto M, Ohkawara T, Sawa Y, Nishida K, Ohkawara Y, Harada Y, Tanaka H, Takamatsu T, Itoh Y. Adenoendocrine cell carcinoma of the gallbladder producing a high level of alpha-fetoprotein. Clin. J. Gastroenterol. 5, 261-267 (2012). Imaizumi K, Harada Y, Wakabayashi N, Yamaoka Y, Konishi H, Dai P, Tanaka H, Takamatsu T. Dual-wavelength excitation of mucosal autofluorescence for precise detection of diminutive colonic adenomas. Gastrointest. Endosc. 75, 110-7 (2012). Nakamura H, Matoba S, Iwai-Kanai E, Kimata M, Hoshino A, Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Okigaki M, Adachi S, Tanaka H, Takamatsu T, Matsubara H. p53 promotes cardiac dysfunction in diabetic mellitus due to excessive mitochondrial respiration-mediated ROS generation and lipid accumulation. Circ. Heart Fail. 5, 106-15 (2012). Murayama M, Ichikawa D, Koizumi N, Komatasu S, Shiozaki A, Kuriu Y, Ikoma H, Kubota T, Nakanishi M, Harada Y, Fujiwara H, Okamoto K, Ochiai T, Kokuba Y, Takamatsu T, Otsuji E. Staging fluorescence laparoscopy for gastric cancer by using 5-aminolevulinic acid. Anticancer Res. 32, 5421-7 (2012). Yamaoka Y, Nambu M, Takamatsu T. Fine depth resolution of two-photon absorption-induced photoacoustic microscopy using low-frequency bandpass filtering. Opt. Express 19, 13365-13377 (2011). Murakami Y, Toyoda H, Tanaka M, Kuroda M, Harada Y, Matsuda F, Tajima A, Kosaka N, Ochiya T, Shimotohno K. The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families. PLoS ONE 6, e16081 (2011). Review articles Puppulin L, Hosogi S, Mochizuki K, Harada Y, Tanaka H Surface Enhanced Raman Spectroscopy for Nanoscale Analyses of Cell Surface Molecular Enrironment J. Spectrosc. Soc. Japan 71, 65-67 (2022) c ` K, c q, ] Y, c G } ɂ 鐶 ̑g D A C A X 2022; 33, 10-14 Kumamoto Y, Harada Y, Takamatsu T, Tanaka H Label-free molecular imaging and analysis by Raman spectroscopy. Acta Histochem. Cytochem. 51, 101-110 (2018). Tanaka H, Matsuyama T, Takamatsu T Towards an integrated understanding of cardiac arrhythmogenesis - Growing roles of expermental pathology. Pathol. Int. 67, 8-16 (2017). c G w @ | ̗ j ƓW ] | @ s { ȑ w G 2017; 126, 785 F { N C c G w @ ̗ j I O s { ȑ w G 2017; 126, 787-796 c ` K } @ s { ȑ w G 2017; 126, 821-828 v h C c ` K C N Y 5- A ~ m u _ p C [ W O Տ 摜2016 @vol.32 No.2 : p245-248 v C i K C q M C J O C c ` K C N Y C | i D } U C [ W O @ ɂ 鑽 F ؔʼn ̐F ޕ q z ͖@ ̊J m w 26, 1-10 (2016). F { N C c G C N Y Âɋ ߂ 鐶 ̌ C [ W O A C A X2016 @vol.27 No.2 Fp1-5 F { N C N Y Õ Ŋ ҂ t H g j N X t H g j N X j [ X2016 @vol.1 No.2 Fp7-11 c ` K C c G C N Y } Ƃ ̈ w E a w ւ̉ p a ƗՏ 2015 vol.33 No.9 Fp1009-1016 N Y a w ɂ 錰 ̗ j a ƗՏ 2015 vol.33 : p422-430 R v C N Y ̐ k ώ@ ̂ ߂̂Q q C [ W O gTECHNO @2015.7 `8 @VOL.27 ANo.4 c G C R v w ̏ Ȏg g D זE w 2014. { g D זE w , pp 127-134. R v C N Y Q q N g ݍ 킹 ̍ ԕ \ o C I C _ X g [2014 N7 ,35-42 i2014 j. c ` K C v C N Y 𗘗p W ̕ q C [ W O G. I. Research 22, 44-49 (2014). ͖ C c ` K C N Y 5- A ~ m u _ ɂ q g p ߓ] ڂ̐v f f G. I. Research 22, 50-56 (2014). v C c ` K C N Y } U ɂ 镪 q C [ W O A C A X, 25 (3), 21-25 (2014) c ` K C N Y p ڎw V Ȏ ƌu C [ W O Z p ̊J זE @THE CELL @P9-12 @vol.46 no.4 2014 c ` K C v C N Y } @ ɂ 鐶 ̏ ̉ OPTRONICS @p70-73 no.389 2014 Harada Y, Takamatsu T. Raman molecular imaging of cells and tissues: towards functional diagnostic imaging without labeling. Curr. Pharm. Biotechnol. 14, 133-140 (2013). Harada Y, Takamatsu T Editional ihot topic: biomedical applications of molecular vibrational imaging j. Curr. Pharm. Biotechnol. 14, 131-132 (2013). c ` K 5 | A ~ m u _ i5-ALA j p ] ڃ p ߂̐f f s { ȑ w G 2013; 122, 181-188 R v C N Y É p 2 q N C [ W O s { ȑ w G 2013; 122, 219-229 v C c ` K C N Y F g D C [ W O ` } U @ p ā` s { ȑ w G 2013; 122, 209-217 R v C N Y ` w ۂ𗘗p ̊J { [ U [ w 2013; 33, 386-391. Harada Y, Takamatsu T Biomedical applications of molecular vibrational imaging. Curr. Pharm. Biotechnol. 14, 131-132 (2012). c ` K C N Y É p ߂ ɂ in vivo q C [ W O w @Vol.30 No.2 191-196 (2012) c ` K C N Y C [ W O ŕa C ݂ Տ a @Vol.60 No.2 119-124 (2012) Yamaoka Y, Takamatsu T. Two-photon absorption-induced photoacoustic microscopy (TP-PAM) to visualize deep structures in living tissues. Optronics 30, 121-125 (2011). MISC Mochizuki K, Tamura S, Morishita Y, Harada Y, Tanaka H. Altering cardiac impulse propagation and generation by local flash photolysis of caged Ca2+. Circ. Res., 135, Suppl_1, We100 (2024). Mochizuki K, Morishita Y, Tamura S, Tanaka H. Local flash photolysis of caged Ca2+ provokes alterations of impulse generation and propagation of cardiac tissue. Proc. SPIE 122160C (2022) Morishita Y, Tamura S, Mochizuki K, Harada Y, Tanaka H. Abnormal Myocyte Calcium Dynamics And The Resultant Contraction Band Formation Of The Rat Heart Under Irreversible Injury By Membrane Permeabilization. Circ. Res., 129, Supple_1, P502 (2021) Books c ` K, ] Y, c G } g D w p p v f f ̉\ p v a f f X ^ _ [ h: ̂̎ 舵 f f ̎ ۂ܂ , pp.63-65 (2024) G, ] Y, c G w ̊ { Ɛ g g D זE w2022 { g D זE w , pp.1-16 (2022) ] Y, c G w ̌ Ɛ g g D זE w2021 { g D זE w , pp.39-53 (2021) G C c G g D w ̊ { ƌ w ώ@ @ g D זE w2019 { g D זE w ҁCpp.31-42 (2019) c ` K C c G w ̎g g D זE w2018 { g D זE w ҁCpp.79-89 (2018) F { N C c G w ̎g - { Ǝ H - g D זE w2017 { g D זE w ҁCpp.111-125 (2017) R _ u a v S ؕp ̂ ׂ ] ( ) Cpp.101-114 R e _ u g ^ S ؏ǁv S ؕp ̂ ׂ ] ( ) Cpp.278-281 A c ] C R @ \ E u z f ÂɊ @ S lj U w v W J r [ z a Z ^ [ a c G w Ȃ g D זE w2015 { g D זE w Cpp.1-10 Minamikawa T, Harada Y, Takamatsu T. Photodynamic detection of lymphnode metastasis in gastrointestinal cancer by using 5-aminolevulinic acid. In: Fluorescence imaging for surgeons. editors, Dip F, Iahizawa T, Kokudo N, Rosenthal RJ. Springer International Publishing: pp.267-278, 2015. Kumamoto Y. Deep-ultraviolet microscopy and microspectroscopy. In: Far- and feep-ultraviolet microscopy. editors, Ozaki Y, Kawata S. Springer Japan: pp.123-144, 2015. N Y 12 z S ̍ V v a w2015 V ( , c, ) ] ( ) Cpp.143-155 c G 12 z ǂ̍ V v a w2015 V ( , c, ) ] ( ) Cpp.156-162 Harada Y, Iwai M, Chang AY. Acute Hepatitis Dignosis of Liver Disease. Pathological Findings, Clinical Manifestations, and Image Analyses. McGraw-Hill Education (Asia)(Singapore), 1-14 (2011) Harada Y, Iwai M, Kwo PY. Acute Liver Failure Dignosis of Liver Disease. Pathological Findings, Clinical Manifestations, and Image Analyses. McGraw-Hill Education (Asia)(Singapore), 15-21 (2011) Takamatsu T, Harada Y, Wakabayashi N, Imaizumi K, Miyawaki K, Nakano K, Yamaoka Y, Yanagisawa A, Yoshikawa T. Highly Fluorescent Macrophages in Colonic Mucosa Under Autofluorescence Imaging Endoscopy: A Brief Case Report New Techniques in Gastrointestinal Endoscopy. 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